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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN6714 | Geranylgeraniol | FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095 | Apoptosis |
Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) ... | |||
T21405 | Fluvastatin | Canef,XU-62320,Vastin,Cranoc,Lescol | HMG-CoA Reductase |
Fluvastatin (XU-62320) is a potent and competitive HMG-CoA reductase inhibitor (IC50: 8 nM) that inhibits oxidative stress in vascular smooth muscle cells through an Nrf2-dependent pathway, and is used for the reduction ... | |||
T40781L1 | Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) | Geranylgeranyl pyrophosphate tetrabutylammonium(1:2)(6699-20-3 Free base) | Others |
Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) is one of the endogenous cholesterol and intermediates produced by the mevalerate pathway. Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) is the common precursor... | |||
T5S0053 | Coptisine | Coptisin | Indoleamine 2,3-Dioxygenase (IDO) |
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ... | |||
T35589 | Geranyl pyrophosphate triammonium | ||
Geranyl pyrophosphate is an intermediate in the mevalonate pathway. It is formed from dimethylallyl pyrophosphate and isopentenyl pyrophosphate by geranyl pyrophosphate synthase. Geranyl pyrophosphate is used in the bios... | |||
T13483 | RP 54275 | 2-Octadecyl-1H-indole-5-carboxylic acid | Others |
RP 54275 is a naturally occurring fatty acid derivative, a new cholesterol-lowering compound. It activates the peroxisome proliferator-activated receptor gamma (PPARγ) pathway, which is involved in the regulation of lipi... | |||
T32825 | L-Mevalonic acid | (S)-Mevalonic acid | Others |
L-Mevalonic acid ((S)-Mevalonic acid), a distant precursor of cholesterol, is a metabolite of the mevalonic acid pathway and is used in the study of autoimmune diseases, atherosclerosis and Alzheimer's disease. | |||
T36536 | SH-42 | ||
SH-42 is an inhibitor of 24-dehydrocholesterol reductase (DHCR24; IC50= 4.2 nM).1It increases serum levels of desmosterol , the immediate precursor of cholesterol in the Bloch pathway, in mice when administered at a dos... | |||
T78081 | Farnesyl Pyrophosphate ammonium | Farnesyl diphosphate ammonium | |
Farnesyl Pyrophosphate Ammonium Salt, a 15-carbon isoprenoid derived from the mevalonate (MVA) pathway, functions as a TRPM2 (TRP Channel) agonist, facilitating the opening of TRPM2 channels for ion influx. It serves as ... | |||
T62052 | AMPK activator 6 | ||
AMPK activator 6 (Compound GC) activates the AMPK pathway and reduces lipid content in HepG2 and 3T3-L1 cells. AMPK activator 6 significantly suppresses the increase of total cholesterol (TC), low-density lipoprotein-C (... | |||
T73755 | Farnesyl pyrophosphate | ||
Farnesyl pyrophosphate (Farnesyl diphosphate), a 15-carbon isoprenoid derived from the mevalonate (MVA) pathway, acts as a metabolic intermediary. It serves as a TRPM2 (TRP Channel) agonist, facilitating the opening of T... |