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Search Results for " cholesterol pathway "

11

Compounds

Cat No. Product Name Synonyms Targets
TN6714 Geranylgeraniol FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095 Apoptosis
Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) ...
T21405 Fluvastatin Canef,XU-62320,Vastin,Cranoc,Lescol HMG-CoA Reductase
Fluvastatin (XU-62320) is a potent and competitive HMG-CoA reductase inhibitor (IC50: 8 nM) that inhibits oxidative stress in vascular smooth muscle cells through an Nrf2-dependent pathway, and is used for the reduction ...
T40781L1 Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) Geranylgeranyl pyrophosphate tetrabutylammonium(1:2)(6699-20-3 Free base) Others
Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) is one of the endogenous cholesterol and intermediates produced by the mevalerate pathway. Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) is the common precursor...
T5S0053 Coptisine Coptisin Indoleamine 2,3-Dioxygenase (IDO)
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ...
T35589 Geranyl pyrophosphate triammonium
Geranyl pyrophosphate is an intermediate in the mevalonate pathway. It is formed from dimethylallyl pyrophosphate and isopentenyl pyrophosphate by geranyl pyrophosphate synthase. Geranyl pyrophosphate is used in the bios...
T13483 RP 54275 2-Octadecyl-1H-indole-5-carboxylic acid Others
RP 54275 is a naturally occurring fatty acid derivative, a new cholesterol-lowering compound. It activates the peroxisome proliferator-activated receptor gamma (PPARγ) pathway, which is involved in the regulation of lipi...
T32825 L-Mevalonic acid (S)-Mevalonic acid Others
L-Mevalonic acid ((S)-Mevalonic acid), a distant precursor of cholesterol, is a metabolite of the mevalonic acid pathway and is used in the study of autoimmune diseases, atherosclerosis and Alzheimer's disease.
T36536 SH-42
SH-42 is an inhibitor of 24-dehydrocholesterol reductase (DHCR24; IC50= 4.2 nM).1It increases serum levels of desmosterol , the immediate precursor of cholesterol in the Bloch pathway, in mice when administered at a dos...
T78081 Farnesyl Pyrophosphate ammonium Farnesyl diphosphate ammonium
Farnesyl Pyrophosphate Ammonium Salt, a 15-carbon isoprenoid derived from the mevalonate (MVA) pathway, functions as a TRPM2 (TRP Channel) agonist, facilitating the opening of TRPM2 channels for ion influx. It serves as ...
T62052 AMPK activator 6
AMPK activator 6 (Compound GC) activates the AMPK pathway and reduces lipid content in HepG2 and 3T3-L1 cells. AMPK activator 6 significantly suppresses the increase of total cholesterol (TC), low-density lipoprotein-C (...
T73755 Farnesyl pyrophosphate
Farnesyl pyrophosphate (Farnesyl diphosphate), a 15-carbon isoprenoid derived from the mevalonate (MVA) pathway, acts as a metabolic intermediary. It serves as a TRPM2 (TRP Channel) agonist, facilitating the opening of T...
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